Article
Genomic predictors of remission to antidepressant treatment in geriatric depression using genome-wide expression analyses: a pilot study.
International journal of geriatric psychiatry - 1 May 2016
Eyre Harris A, Eskin Ascia, Nelson Stanley F, St Cyr Natalie M, Siddarth Prabha, Baune Bernhard T, Lavretsky Helen
Abstract excerpt
OBJECTIVE: This first pilot study of genome-wide expression as predictor of antidepressant response in late-life depression examined genome-wide transcriptional profiles in a randomized placebo-controlled trial of combined methylphenidate and citalopram. METHODS: Genome-wide transcriptional profiles were examined in peripheral blood leukocytes sampled at baseline and 16 weeks from 35 older adults with major...
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