Article
Clinical outcomes and genome-wide association for a brain methylation site in an antidepressant pharmacogenetics study in Mexican Americans.
The American journal of psychiatry - 1 Dec 2014
Wong Ma-Li, Dong Chuanhui, Flores Deborah L, Ehrhart-Bornstein Monika, Bornstein Stefan, Arcos-Burgos Mauricio, Licinio Julio
Abstract excerpt
OBJECTIVE: The authors compared the effectiveness of fluoxetine and desipramine treatment in a prospective double-blind pharmacogenetics study in first-generation Mexican Americans and examined the role of whole-exome functional gene variations in the patients' antidepressant response. METHOD: A total of 232 Mexican Americans who met DSM-IV criteria for major depressive disorder were randomly assigned to receive...
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