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Treatment-emergent and trajectory-based peripheral gene expression markers of antidepressant response

21 Aug 2021

Abstract excerpt

Identifying biomarkers of antidepressant response may advance personalized treatment of major depressive disorder (MDD). We aimed to identify longitudinal changes in gene expression associated with response to antidepressants in a sample of MDD patients treated with escitalopram. Patients (N = 153) from the CAN-BIND-1 cohort were treated for 8 weeks, and depressive symptoms were assessed using the...

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PMID: 34420030
DOI: 10.1038/s41398-021-01564-8

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