Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Blood-based DNA methylation of DNA repair genes in the non-homologous end-joining (NEHJ) pathway in patient with glioma.

International journal of clinical and experimental pathology - 1 Jan 2015

Zhou Chengcheng, Tang Hailiang, Yu Jian, Zhuang Dongxiao, Zhang Haishi

Abstract excerpt

UNLABELLED: To investigate the blood-based DNA methylation of repair genes including LIG4, XRCC4, XRCC5, XRCC6 and XRCC7 that involved in non-homologous end-joining (NEHJ) DNA repair pathway in patients with glioma. Blood samples were obtained from 114 glioma patients, 96 normal controls, and 81 glioma patients after radiotherapy and chemotherapy. Blood-based DNA methylation of the five NHEJ repair genes was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Nuclear
Share to DNA-Activated Protein Kinase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA End-Joining Repair

Share to DNA Helicases

Share to DNA Ligase ATP

Share to DNA Ligases

Share to Glioma

Share to Ku Autoantigen

Source

Open in PubMed Open full text

Identifiers

PMID: 26464705
PMCID: PMC4583937

Genes

XRCC5
LIG4
XRCC4
XRCC6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Blood-based DNA methylation of DNA repair genes in the non-homologous end-joining (NEHJ) pathway in patient with glioma.PMID 26464705Read ↗

The Impact of Hedgehog Signaling Pathway on DNA Repair Mechanisms in Human CancerSemantic proximity Read ↗

Involvement of classic and alternative non-homologous end joining pathways in hematologic malignancies: targeting strategies for treatmentSemantic proximity Read ↗

Tagging SNPs in non-homologous end-joining pathway genes and risk of glioma.Semantic proximity Read ↗

Polymorphisms of DNA Repair Genes and Risk of GliomaSemantic proximity Read ↗

Genetic polymorphisms in XRCC1 gene and susceptibility to glioma in Chinese Han population.Semantic proximity Read ↗

[Correlation of polymorphisms of DNA double-strand break repair genes XRCC5, LIG4 and glioma].Semantic proximity Read ↗

The pivotal role of DNA methylation in the radio‐sensitivity of tumor radiotherapySemantic proximity Read ↗

Association of LIG4 and XRCC4 gene polymorphisms with the risk of human glioma in a Chinese population.Semantic proximity Read ↗

Quantitative assessment of the association between XRCC3 C18607T polymorphism and glioma risk.Semantic proximity Read ↗

Polymorphisms of LIG4 and XRCC4 involved in the NHEJ pathway interact to modify risk of glioma.Semantic proximity Read ↗

The relationship between polymorphisms of XRCC5 genes with astrocytoma prognosis in the Han Chinese population.Semantic proximity Read ↗

Genetic effects of XRCC4 and ligase IV genes on human glioma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.