Article
Genetic risk score based on the lifetime prevalence of femoral fracture in 924 consecutive autopsies of Japanese males.
Journal of bone and mineral metabolism - 1 Nov 2016
Zhou Heying, Mori Seijiro, Ishizaki Tatsuro, Tanaka Masashi, Tanisawa Kumpei, Mieno Makiko Naka, Sawabe Motoji, Arai Tomio, Muramatsu Masaaki, Yamada Yoshiji, Ito Hideki
Abstract excerpt
A genetic risk score (GRS) was developed for predicting fracture risk based on lifetime prevalence of femoral fractures in 924 consecutive autopsies of Japanese males. A total of 922 non-synonymous single nucleotide polymorphisms (SNPs) located in 62 osteoporosis susceptibility genes were genotyped and evaluated for their association with the prevalence of femoral fracture in autopsy cases. GRS values were...
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