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Article

Endothelin B receptor gene hypermethylation in prostate adenocarcinoma: Figure 1

23 Dec 2002

Abstract excerpt

BACKGROUND: Alterations in the methylation patterns of promoter CpG islands have been associated with the transcriptional inhibition of genes in many human cancers. These epigenetic alterations could be used as molecular markers for the early detection of cancer-that is, while potentially curable according to current therapeutic strategies. In prostate cancer, GSTP1 hypermethylation is the most common epigenetic...

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PMID: 12499435
DOI: 10.1136/jcp.56.1.52

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