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Article

Poly(ADP-ribosyl)ation as a new posttranslational modification of YB-1.

Biochimie - 1 Dec 2015

Alemasova Elizaveta E, Pestryakov Pavel E, Sukhanova Maria V, Kretov Dmitry A, Moor Nina A, Curmi Patrick A, Ovchinnikov Lev P, Lavrik Olga I

Abstract excerpt

Multifunctional Y-box binding protein 1 (YB-1) is actively studied as one of the components of cellular response to genotoxic stress. However, the precise role of YB-1 in the process of DNA repair is still obscure. In the present work we report for the first time new posttranslational modification of YB-1 - poly(ADP-ribosyl)ation, catalyzed by one of the main regulatory enzymes of DNA repair -...

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Source

Identifiers

PMID: 26453809
DOI: 10.1016/j.biochi.2015.10.008

Genes

PARP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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