Article
Contribution of GABRG2 Polymorphisms to Risk of Epilepsy and Febrile Seizure: a Multicenter Cohort Study and Meta-analysis.
Molecular neurobiology - 1 Oct 2016
Haerian Batoul Sadat, Baum Larry, Kwan Patrick, Cherny Stacey S, Shin Jae-Gook, Kim Sung Eun, Han Bok-Ghee, Tan Hui Jan, Raymond Azman Ali, Tan Chong Tin, Mohamed Zahurin
Abstract excerpt
Gamma-aminobutyric acid receptor (GABA-A) is the most common receptor of fast synaptic inhibition in the human brain. Gamma protein encoded by the GABRG2 gene is one of the subunits of the GABA-A receptor, which plays an essential role in the function of this receptor. Several studies have identified various febrile seizure (FS) and epilepsy risk variants of GABRG2 gene in different populations, but some others...
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