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Article

Analysis of GABRG2 C588T polymorphism in genetic epilepsy and evaluation of GABRG2 in drug treatment.

Clinical and translational science - 1 Sept 2021

Wang Shitao, Zhang Xianjun, Zhou Liang, Wu Qian, Han Yanbing

Abstract excerpt

Epilepsy is a common disorder with complex inheritance, and its treatment is very unsatisfactory. An association between the GABRG2 C588T polymorphism and genetic generalized epilepsy has been studied by several genetic association studies. However, these results were inconsistent, and the role of GABRG2 in epilepsy treatment remains unknown. To evaluate the role of GABRG2 in epilepsy, we performed meta-analysis,...

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Identifiers

PMID: 33650258
DOI: 10.1111/cts.12997
PMCID: PMC8504831

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