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Article

GABRG2 Variants Associated with Febrile Seizures.

Biomolecules - 22 Feb 2023

Hernandez Ciria C, Shen Yanwen, Hu Ningning, Shen Wangzhen, Narayanan Vinodh, Ramsey Keri, He Wen, Zou Liping, Macdonald Robert L

Abstract excerpt

Febrile seizures (FS) are the most common form of epilepsy in children between six months and five years of age. FS is a self-limited type of fever-related seizure. However, complicated prolonged FS can lead to complex partial epilepsy. We found that among the GABAA receptor subunit (GABR) genes, most variants associated with FS are harbored in the γ2 subunit (GABRG2). Here, we characterized the effects of eight...

Topics

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Epilepsies, Myoclonic
Epilepsy
Epilepsy research and treatment
Mutation
Mutation, Missense

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neuroscience and Neuropharmacology Research

Receptors, GABA-A

Seizures, Febrile

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Identifiers

PMID: 36979350
DOI: 10.3390/biom13030414
PMCID: PMC10046037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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