Article
Association between the gamma-aminobutyric acid type B receptor 1 and 2 gene polymorphisms and mesial temporal lobe epilepsy in a Han Chinese population.
Epilepsy research - 1 Oct 2008
Wang Xin, Sun Wei, Zhu Xilin, Li Liping, Wu Xiaopan, Lin Hua, Zhu Shuying, Liu Aihua, Du Te, Liu Yang, Niu Nifang, Wang Yuping, Liu Ying
Abstract excerpt
An abnormal gamma-aminobutyric acid B receptor composed of gamma-aminobutyric acid type B receptor 1 (GABBR1) and gamma-aminobutyric acid type B receptor 2 (GABBR2) can provoke seizures. This study was designed to assess the contribution of GABBR1 and GABBR2 in mesial temporal lobe epilepsy (MTLE). Two tag single-nucleotide polymorphisms (SNPs) of GABBR1 and four tag SNPs of GABBR2 were selected and genotyped in...
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