Article
Polymorphisms in HLA Class II Genes Are Associated With Susceptibility to Staphylococcus aureus Infection in a White Population.
The Journal of infectious diseases - 1 Mar 2016
DeLorenze Gerald N, Nelson Charlotte L, Scott William K, Allen Andrew S, Ray G Thomas, Tsai Ai-Lin, Quesenberry Charles P, Fowler Vance G
Abstract excerpt
BACKGROUND: Staphylococcus aureus can cause life-threatening infections. Human susceptibility to S. aureus infection may be influenced by host genetic variation. METHODS: A genome-wide association study (GWAS) in a large health plan-based cohort included biologic specimens from 4701 culture-confirmed S. aureus cases and 45 344 matched controls; 584 535 single-nucleotide polymorphisms (SNPs) were genotyped on an...
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