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Article

Elevated risk of invasive group A streptococcal disease and host genetic variation in the human leukocyte antigen locus

2019-02-24

Abstract excerpt

Invasive group A streptococcal (GAS) disease is uncommon but carries a high case-fatality rate relative to other infectious diseases. Given the ubiquity of mild GAS infections, it remains unclear why healthy individuals will occasionally develop life-threatening infections, raising the possibility of host genetic predisposition. Here, we present the results of a case-control study including 43 invasive GAS cases a...

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Literature Corpus work
a5f08892-7b43-5b4d-bcfe-65e695eb6fbb
DOI
10.1101/559161
Open publication

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Elevated risk of invasive group A streptococcal disease and host genetic variation in the human leukocyte antigen locusDOI 10.1101/559161
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