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IGF-1 Peptide Mimetic-functionalized Hydrogels Enhance MSC Survival and Immunomodulatory Activity

2024-07-02

Abstract excerpt

Human mesenchymal stem cells (MSCs) have demonstrated promise when delivered to damaged tissue or tissue defects for their cytokine secretion and inflammation modulation behaviors that can promote repair. Insulin-like growth factor 1 (IGF-1) has been shown to augment MSCs’ viability and survival and promote their secretion of cytokines that signal to endogenous cells, in the treatment of myocardial infarction, wou...

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Literature Corpus work
7247c65f-0585-5827-9e3d-31cffe2ee1c1
DOI
10.1101/2024.06.27.600680
Open publication

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IGF-1 Peptide Mimetic-functionalized Hydrogels Enhance MSC Survival and Immunomodulatory ActivityDOI 10.1101/2024.06.27.600680
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