Article
Incorporation of biomaterials in multicellular aggregates modulates pluripotent stem cell differentiation.
Biomaterials - 1 Jan 2011
Bratt-Leal Andrés M, Carpenedo Richard L, Ungrin Mark D, Zandstra Peter W, McDevitt Todd C
Abstract excerpt
Biomaterials are increasingly being used to engineer the biochemical and biophysical properties of the extracellular stem cell microenvironment in order to tailor niche characteristics and direct cell phenotype. To date, stem cell-biomaterial interactions have largely been studied by introducing stem cells into artificial environments, such as 2D cell culture on biomaterial surfaces, encapsulation of cell...
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