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Article

The collagen I mimetic peptide DGEA enhances an osteogenic phenotype in mesenchymal stem cells when presented from cell-encapsulating hydrogels.

Journal of biomedical materials research. Part A - 1 Nov 2015

Mehta Manav, Madl Christopher M, Lee Shimwoo, Duda Georg N, Mooney David J

Abstract excerpt

Interactions between cells and the extracellular matrix (ECM) are known to play critical roles in regulating cell phenotype. The identity of ECM ligands presented to mesenchymal stem cells (MSCs) has previously been shown to direct the cell fate commitment of these cells. To enhance osteogenic differentiation of MSCs, alginate hydrogels were prepared that present the DGEA ligand derived from collagen I. When...

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Identifiers

PMID: 25953514
DOI: 10.1002/jbm.a.35497
PMCID: PMC4589437

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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