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Article

Association of orexin receptor polymorphisms with antipsychotic-induced weight gain.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Apr 2016

Tiwari Arun K, Brandl Eva J, Zai Clement C, Goncalves Vanessa F, Chowdhury Nabilah I, Freeman Natalie, Lieberman Jeffrey A, Meltzer Herbert Y, Kennedy James L, Müller Daniel J

Abstract excerpt

OBJECTIVES: Antipsychotic-induced weight gain (AIWG) is a common side effect of treatment with antipsychotics such as clozapine and olanzapine. The orexin gene and its receptors are expressed in the hypothalamus and have been associated with maintenance of energy homeostasis. In this study, we have analysed tagging single nucleotide polymorphisms (SNPs) in orexin receptors 1 and 2 (HCRTR1 and HCRTR2) for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26447462
DOI: 10.3109/15622975.2015.1076173

Genes

HCRTR2
HCRTR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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