Article
Introduction to the analysis of next generation sequencing data and its application to venous thromboembolism.
Thrombosis and haemostasis - 1 Nov 2015
Cunha Marisa L R, Meijers Joost C M, Middeldorp Saskia
Abstract excerpt
Despite knowledge of various inherited risk factors associated with venous thromboembolism (VTE), no definite cause can be found in about 50% of patients. The application of data-driven searches such as GWAS has not been able to identify genetic variants with implications for clinical care, and unexplained heritability remains. In the past years, the development of several so-called next generation sequencing...
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