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Article

Identification of genetic risk variants for deep vein thrombosis by multiplexed next-generation sequencing of 186 hemostatic/pro-inflammatory genes.

BMC medical genomics - 21 Feb 2012

Lotta Luca A, Wang Mark, Yu Jin, Martinelli Ida, Yu Fuli, Passamonti Serena M, Consonni Dario, Pappalardo Emanuela, Menegatti Marzia, Scherer Steven E, Lewis Lora L, Akbar Humeira, Wu Yuanqing, Bainbridge Matthew N, Muzny Donna M, Mannucci Pier M, Gibbs Richard A, Peyvandi Flora

Abstract excerpt

BACKGROUND: Next-generation DNA sequencing is opening new avenues for genetic association studies in common diseases that, like deep vein thrombosis (DVT), have a strong genetic predisposition still largely unexplained by currently identified risk variants. In order to develop sequencing and analytical pipelines for the application of next-generation sequencing to complex diseases, we conducted a pilot study...

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PMID: 22353194
DOI: 10.1186/1755-8794-5-7
PMCID: PMC3305575

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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