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Article

Changing preferences: deformation of single position amino acid fitness landscapes and evolution of proteins.

Biology letters - 1 Oct 2015

Bazykin Georgii A

Abstract excerpt

The fitness landscape-the function that relates genotypes to fitness-and its role in directing evolution are a central object of evolutionary biology. However, its huge dimensionality precludes understanding of even the basic aspects of its shape. One way to approach it is to ask a simpler question: what are the properties of a function that assigns fitness to each possible variant at just one particular site-a...

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Source

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Identifiers

PMID: 26445980
DOI: 10.1098/rsbl.2015.0315
PMCID: PMC4650171

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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