Article
In Vitro Macrophage Phagocytosis Assay.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015
Hamczyk Magda R, Villa-Bellosta Ricardo, Andrés Vicente
Abstract excerpt
The key roles of macrophages in atherosclerosis include the phagocytosis of apoptotic and necrotic cells and cell debris, whose accumulation in atherosclerotic lesions exacerbates inflammation and promotes plaque vulnerability. Evidence is accumulating that macrophage phagocytic functions peak at the early stages of atherosclerosis and that the reduced phagocytosis at the late stages of disease leads to the...
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