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Article

Prevalence of genetic polymorphisms of CYP2C9 and VKORC1 - implications for warfarin management and outcome in Croatian patients with acute stroke.

Journal of the neurological sciences - 15 Aug 2014

Supe Svjetlana, Božina Nada, Matijević Vesna, Bazina Antonela, Mišmaš Antonija, Ljevak Josip, Alvir Domagoj, Habek Mario, Poljaković Zdravka

Abstract excerpt

BACKGROUND: Data on the prevalence of CYP2C9 and VKORC1 genes and their influence on anticoagulant effect and warfarin dose in stroke patients are scarce. The aim of this study was to determine the occurrence and significance of these gene polymorphisms and to establish pharmacogenetic algorithm to estimate the dose of introduction. Also, the goal was to determine tailored safety and intensity of anticoagulation...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2C9

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Share to Statistics, Nonparametric

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Share to Vitamin K Epoxide Reductases

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Source

Identifiers

PMID: 24974237
DOI: 10.1016/j.jns.2014.04.039

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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