Article
Beyond gene discovery in inflammatory bowel disease: the emerging role of epigenetics.
Gastroenterology - 1 Aug 2013
Ventham Nicholas T, Kennedy Nicholas A, Nimmo Elaine R, Satsangi Jack
Abstract excerpt
In the past decade, there have been fundamental advances in our understanding of genetic factors that contribute to the inflammatory bowel diseases (IBDs) Crohn's disease and ulcerative colitis. The latest international collaborative studies have brought the number of IBD susceptibility gene loci to 163. However, genetic factors account for only a portion of overall disease variance, indicating a need to better...
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