Article
Left ventricular outflow tract gradient is associated with reduced capillary density in hypertrophic cardiomyopathy irrespective of genotype.
European journal of clinical investigation - 1 Dec 2015
Güçlü Ahmet, Happé Chris, Eren Seyma, Korkmaz Ibrahim H, Niessen Hans W M, Klein Patrick, van Slegtenhorst Marjon, Schinkel Arend F, Michels Michelle, van Rossum Albert C, Germans Tjeerd, van der Velden Jolanda
Abstract excerpt
BACKGROUND: Coronary microvascular dysfunction (CMD) is an important feature of hypertrophic cardiomyopathy (HCM), which contributes negatively to symptoms and long-term outcome. Previous in vivo imaging studies in HCM suggest that left ventricular outflow tract (LVOT) gradient and genetic status are important contributors to CMD. CMD may be caused by reduced capillary density. Here, we investigated whether a...
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