Article
Carriers of the hypertrophic cardiomyopathy MYBPC3 mutation are characterized by reduced myocardial efficiency in the absence of hypertrophy and microvascular dysfunction.
European journal of heart failure - 1 Dec 2011
Timmer Stefan A J, Germans Tjeerd, Brouwer Wessel P, Lubberink Mark, van der Velden Jolanda, Wilde Arthur A M, Christiaans Imke, Lammertsma Adriaan A, Knaapen Paul, van Rossum Albert C
Abstract excerpt
AIMS: Next to left ventricular (LV) hypertrophy, hypertrophic cardiomyopathy (HCM) is characterized by microvascular dysfunction and reduced myocardial external efficiency (MEE). Insights into the presence of these abnormalities as early markers of disease are of clinical importance in risk stratification, and development of therapeutic approaches. Therefore, the aim was to investigate myocardial perfusion and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.