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Article

Microvascular function is selectively impaired in patients with hypertrophic cardiomyopathy and sarcomere myofilament gene mutations.

Journal of the American College of Cardiology - 16 Aug 2011

Olivotto Iacopo, Girolami Francesca, Sciagrà Roberto, Ackerman Michael J, Sotgia Barbara, Bos J Martijn, Nistri Stefano, Sgalambro Aurelio, Grifoni Camilla, Torricelli Francesca, Camici Paolo G, Cecchi Franco

Abstract excerpt

OBJECTIVES: The purpose of this study was to assess myocardial blood flow (MBF) using positron emission tomography in patients with hypertrophic cardiomyopathy (HCM) according to genetic status. BACKGROUND: Coronary microvascular dysfunction is an important feature of HCM, associated with ventricular remodeling and heart failure. We recently demonstrated the increased prevalence of systolic dysfunction in...

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Identifiers

PMID: 21835320
DOI: 10.1016/j.jacc.2011.05.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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