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Article

Heptyl prodigiosin, a bacterial metabolite, is antimalarial in vivo and non-mutagenic in vitro.

Journal of natural toxins - 1 Dec 2002

Lazaro J Enrico H, Nitcheu Josiane, Predicala Rey Z, Mangalindan Gina C, Nesslany Fabrice, Marzin Daniel, Concepcion Gisela P, Diquet Bertrand

Abstract excerpt

Heptyl prodigiosin was purified from a culture of alpha-proteobacteria isolated from a marine tunicate collected in Zamboanga, Philippines, as part of a program to screen natural products for antiparasitic activity. An in vitro antimalarial activity similar to that of quinine was found against the chloroquine-sensitive strain Plasmodium falciparum 3D7. The in vitro antimalarial activity was about 20 times the in...

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PMID: 12503881

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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