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wKinMut-2: Identification and Interpretation of Pathogenic Variants in Human Protein Kinases.

Human mutation - 1 Jan 2016

Vazquez Miguel, Pons Tirso, Brunak Søren, Valencia Alfonso, Izarzugaza Jose M G

Abstract excerpt

Most genomic alterations are tolerated while only a minor fraction disrupts molecular function sufficiently to drive disease. Protein kinases play a central biological function and the functional consequences of their variants are abundantly characterized. However, this heterogeneous information is often scattered across different sources, which makes the integrative analysis complex and laborious. wKinMut-2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26443060
DOI: 10.1002/humu.22914

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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