Article
wKinMut: an integrated tool for the analysis and interpretation of mutations in human protein kinases.
BMC bioinformatics - 29 Nov 2013
Izarzugaza Jose M G, Vazquez Miguel, del Pozo Angela, Valencia Alfonso
Abstract excerpt
BACKGROUND: Protein kinases are involved in relevant physiological functions and a broad number of mutations in this superfamily have been reported in the literature to affect protein function and stability. Unfortunately, the exploration of the consequences on the phenotypes of each individual mutation remains a considerable challenge. RESULTS: The wKinMut web-server offers direct prediction of the potential...
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