Article
DC-SIGN expression on podocytes and its role in inflammatory immune response of lupus nephritis.
Clinical and experimental immunology - 1 Mar 2016
Cai Minchao, Zhou Tong, Wang Xuan, Shang Minghua, Zhang Yueyue, Luo Maocai, Xu Chundi, Yuan Weijie
Abstract excerpt
Podocytes, the main target of immune complex, participate actively in the development of glomerular injury as immune cells. Dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN) is an innate immune molecular that has an immune recognition function, and is involved in mediation of cell adhesion and immunoregulation. Here we explored the expression of DC-SIGN on podocytes and its...
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