Article
The 14-3-3 Gene Function of Cryptococcus neoformans Is Required for its Growth and Virulence.
Journal of microbiology and biotechnology - 28 May 2016
Li Jingbo, Chang Yun C, Wu Chun-Hua, Liu Jennifer, Kwon-Chung Kyung J, Huang Sheng-He, Shimada Hiro, Fante Rob, Fu Xiaowei, Jong Ambrose
Abstract excerpt
Cryptococcus neoformans is a life-threatening pathogenic yeast that causes devastating meningoencephalitis. The mechanism of cryptococcal brain invasion is largely unknown, and recent studies suggest that its extracellular microvesicles may be involved in the invasion process. The 14-3-3 protein...
Topics
- 14-3-3 Proteins
- Acid Phosphatase
- Biomarkers
- Brain
- Cell Adhesion
- Copper
- Cryptococcus neoformans
- Endothelial Cells
- Fungal Capsules
- Fungal Proteins
- Humans
- Laccase
- Mutation
- Phenotype
- Promoter Regions, Genetic
- Virulence
- Virulence Factors
