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Article

The 14-3-3 Gene Function of Cryptococcus neoformans Is Required for its Growth and Virulence.

Journal of microbiology and biotechnology - 28 May 2016

Li Jingbo, Chang Yun C, Wu Chun-Hua, Liu Jennifer, Kwon-Chung Kyung J, Huang Sheng-He, Shimada Hiro, Fante Rob, Fu Xiaowei, Jong Ambrose

Abstract excerpt

Cryptococcus neoformans is a life-threatening pathogenic yeast that causes devastating meningoencephalitis. The mechanism of cryptococcal brain invasion is largely unknown, and recent studies suggest that its extracellular microvesicles may be involved in the invasion process. The 14-3-3 protein is abundant in the extracellular microvesicles of C. neoformans, and the 14-3-3-GFP fusion has been used as the...

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PMID: 26437944
DOI: 10.4014/jmb.1508.08051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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