Effect of scavenger receptor class B type I antagonist ITX5061 in patients with hepatitis C virus infection undergoing liver transplantation.

doi:10.1002/lt.24349

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Article

Effect of scavenger receptor class B type I antagonist ITX5061 in patients with hepatitis C virus infection undergoing liver transplantation.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society - 1 Mar 2016

Rowe Ian A, Tully Damien C, Armstrong Matthew J, Parker Richard, Guo Kathy, Barton Darren, Morse Gene D, Venuto Charles S, Ogilvie Colin B, Hedegaard Ditte L, McKelvy Jeffrey F, Wong-Staal Flossie, Allen Todd M, Balfe Peter, McKeating Jane A, Mutimer David J

Abstract excerpt

Hepatitis C virus (HCV) entry inhibitors have been hypothesized to prevent infection of the liver after transplantation. ITX5061 is a scavenger receptor class B type I antagonist that blocks HCV entry and infection in vitro. We assessed the safety and efficacy of ITX5061 to limit HCV infection of the graft. The study included 23 HCV-infected patients undergoing liver transplantation. The first 13 "control"...

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Identifiers

PMID: 26437376
DOI: 10.1002/lt.24349
PMCID: PMC4901184

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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