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Characterization of the inhibition of hepatitis C virus entry by in vitro-generated and patient-derived oxidized low-density lipoprotein.

Hepatology (Baltimore, Md.) - 1 May 2013

Westhaus Sandra, Bankwitz Dorothea, Ernst Stefanie, Rohrmann Katrin, Wappler Ilka, Agné Clemens, Luchtefeld Maren, Schieffer Bernhard, Sarrazin Christoph, Manns Michael P, Pietschmann Thomas, Ciesek Sandra, von Hahn Thomas

Abstract excerpt

UNLABELLED: Oxidized low-density lipoprotein (oxLDL) has been reported as an inhibitor of hepatitis C virus (HCV) cell entry, making it the only known component of human lipid metabolism with an antiviral effect on HCV. However, several questions remain open, including its effect on full-length cell-culture-grown HCV (HCVcc) of different genotypes or on other steps of the viral replication cycle, its mechanism of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23212706
DOI: 10.1002/hep.26190

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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