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Article

Protein-caloric dietary restriction inhibits mossy fiber sprouting in the pilocarpine model of TLE without significantly altering seizure phenotype.

Epilepsy research - 1 Nov 2015

Rezende Gustavo Henrique Souza, Guidine Patrícia Alves Maia, Medeiros Daniel de Castro, Moraes-Santos Tasso, Mello Luiz Eugênio, Moraes Márcio Flávio Dutra

Abstract excerpt

Given the known effects of undernutrition over protein synthesis, we promoted neonatal undernutrition to evaluate its effect over the neuroplasticity induced by the pilocarpine model of epilepsy and also over spontaneous seizure expression. A well-nourished group (WN), fed ad libitum rat chow diet, and an undernourished group (UN), fed 60% of the amount of diet consumed by a WN group, were submitted to status...

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Identifiers

PMID: 26432758
DOI: 10.1016/j.eplepsyres.2015.08.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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