Article
Seizure prophylaxis in an animal model of epilepsy by dietary fluoxetine supplementation.
Epilepsy research - 1 Apr 2007
Richman Alyssa, Heinrichs Stephen C
Abstract excerpt
Clinical and animal model evidence suggests that selective serotonin reuptake inhibitors (SSRIs) act as anticonvulsants. The present studies tested the possibility that the El mouse model of genetically predisposed/handling-triggered epilepsy would exhibit fewer seizures following SSRI treatment via dietary fluoxetine adulteration. In particular, potential bioenergetic and neural mechanisms for anticonvulsant...
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