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A Genomics-Based Classification of Human Lung Tumors

30 Oct 2013

Abstract excerpt

We characterized genome alterations in 1255 clinically annotated lung tumors of all histological subgroups to identify genetically defined and clinically relevant subtypes. More than 55% of all cases had at least one oncogenic genome alteration potentially amenable to specific therapeutic intervention, including several personalized treatment approaches that are already in clinical evaluation. Marked differences...

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PMID: 24174329
DOI: 10.1126/scitranslmed.3006802

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