Article
Molecular Pathology of Lung Cancer.
Cold Spring Harbor perspectives in medicine - 1 Mar 2022
J Saller James, Boyle Theresa A
Abstract excerpt
This overview of the molecular pathology of lung cancer includes a review of the most salient molecular alterations of the genome, transcriptome, and the epigenome. The insights provided by the growing use of next-generation sequencing (NGS) in lung cancer will be discussed, and interrelated concepts such as intertumor heterogeneity, intratumor heterogeneity, tumor mutational burden, and the advent of liquid...
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