Article
Cationic Peptides Facilitate Iron-induced Mutagenesis in Bacteria.
PLoS genetics - 1 Oct 2015
Rodríguez-Rojas Alexandro, Makarova Olga, Müller Uta, Rolff Jens
Abstract excerpt
Pseudomonas aeruginosa is the causative agent of chronic respiratory infections and is an important pathogen of cystic fibrosis patients. Adaptive mutations play an essential role for antimicrobial resistance and persistence. The factors that contribute to bacterial mutagenesis in this environment are not clear. Recently it has been proposed that cationic antimicrobial peptides such as LL-37 could act as mutagens...
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