Article
The Pseudomonas aeruginosa pfpI gene plays an antimutator role and provides general stress protection.
Journal of bacteriology - 1 Feb 2009
Rodríguez-Rojas Alexandro, Blázquez Jesús
Abstract excerpt
Hypermutator Pseudomonas aeruginosa strains, characterized by an increased spontaneous-mutation rate, are found at high frequencies in chronic lung infections. Hypermutability is associated with the loss of antimutator genes related to DNA repair or damage avoidance systems. Only a few antimutator genes have been described in P. aeruginosa, although there is some evidence that additional genes may be involved in...
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