Article
Genomic analysis of Fas and FasL genes and absence of correlation with disease progression in AIDS.
Immunogenetics - 1 Apr 2004
Vasilescu A, Heath S C, Diop G, Do H, Hirtzig T, Hendel H, Bertin-Maghit S, Rappaport J, Therwath A, Lathrop G M, Matsuda F, Zagury J-F
Abstract excerpt
Apoptosis has been suggested as a major mechanism for the CD4(+) T-lymphocyte depletion observed in patients infected with human immunodeficiency virus 1 (HIV-1). To evaluate the impact of genetic variations to apoptosis during progression of acquired immunodeficiency syndrome (AIDS), we have per...
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