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Article

Role of the Fas/FasL Pathway in HIV or SIV Disease

15 Oct 2009

Abstract excerpt

Human immunodeficiency virus disease involves progressive destruction of host immunity leading to opportunistic infections and increased rates for malignancies. Both depletion in immune cell numbers as well as defects in their effector functions are responsible for this immunodeficiency The broad impact of HIV reflects a similarly broad pattern of cell depletion including subsets that do not express viral...

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PMID: 19832988
DOI: 10.1186/1742-4690-6-91

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