Article
Association of a coding polymorphism in Fc gamma receptor 2A and graft survival in re-transplant candidates.
Human immunology - 1 Oct 2015
Arnold Marie-Luise, Fuernrohr Barbara G, Weiß Katrin M, Harre Ulrike, Wiesener Michael S, Spriewald Bernd M
Abstract excerpt
The family of Fc gamma receptors (FcγRs) is involved in mediating immunological effector functions. FcγRs are differentially expressed on immune cells and can act either activating or inhibitory, with FcγR2A belonging to the first group. The polymorphism H131R (rs1801274) in FCGR2A has been associated with acute rejection and can shift the overall balance between activating and inhibitory FcγRs. Anti-HLA...
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