Article
Molecular profiling of estrogen receptor α and progesterone receptor transcript variants in endometrial cancer.
Steroids - 1 Dec 2015
Skrzypczak Maciej, Merx Isabel, Schüler-Toprak Susanne, Weber Florian, Inwald Elisabeth C, Ortmann Olaf, Treeck Oliver
Abstract excerpt
The human genes coding for estrogen receptor alpha (ERα) and progesterone receptor (PR) express multiple receptor splice variants. Some of these receptor variants previously have been shown to exert distinct functions in cancer cells and might therefore differentially affect individual prognosis or therapy response. To examine the role of ERα- and PR-isoforms in endometrial cancer, we compared the expression of...
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