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Article

Estrogen receptor alpha mRNA variant lacking exon 5 is co-expressed with the wild-type in endometrial adenocarcinoma.

European journal of obstetrics, gynecology, and reproductive biology - 10 Apr 2002

Cobellis Luigi, Reis Fernando M, Driul Lorenza, Vultaggio Giuseppe, Ferretti Ilva, Villa Erica, Petraglia Felice

Abstract excerpt

BACKGROUND: Endometrial adenocarcinoma is a typical estrogen-dependent neoplasia. The molecular mechanisms underlying carcinogenesis in the endometrium are still largely unknown. Recently, estrogen receptor (ER) mRNA splicing variants have been investigated in several normal and neoplastic human tissues. It has been suggested that the variant receptors compete with the wild-type receptors and thereby modulate the...

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PMID: 12039098
DOI: 10.1016/s0301-2115(01)00576-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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