Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intraflagellar transport is essential for mammalian spermiogenesis but is absent in mature sperm

1 Oct 2015

Abstract excerpt

Drosophila sperm are unusual in that they do not require the intraflagellar transport (IFT) system for assembly of their flagella. In the mouse, the IFT proteins are very abundant in testis, but we here show that mature sperm are completely devoid of them, making the importance of IFT to mammalian sperm development unclear. To address this question, we characterized spermiogenesis and fertility in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Kidney Cyst Diseases
Share to Renal and related cancers
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26424803
DOI: 10.1091/mbc.e15-08-0578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Intraflagellar transport is essential for mammalian spermiogenesis but is absent in mature spermPMID 26424803Read ↗

The essential role of intraflagellar transport protein IFT81 in male mice spermiogenesis and fertilitySemantic proximity Read ↗

Intraflagellar transporter protein 140 (IFT140), a component of IFT‐A complex, is essential for male fertility and spermiogenesis in miceSemantic proximity Read ↗

IFT25, an intraflagellar transporter protein dispensable for ciliogenesis in somatic cells, is essential for sperm flagella formation†Semantic proximity Read ↗

Intraflagellar transport protein 74 is essential for mouse spermatogenesis and male fertility by regulating axonemal microtubule assembly in miceSemantic proximity Read ↗

Murine germ cell-specific disruption of Ift172 causes defects in spermiogenesis and male fertilitySemantic proximity Read ↗

Knockout mouse models of sperm flagellum anomaliesSemantic proximity Read ↗

Bi-allelic mutation in Fsip1 impairs acrosome vesicle formation and attenuates flagellogenesis in mice.Semantic proximity Read ↗

Coiled-coil domain-containing 38 is required for acrosome biogenesis and fibrous sheath assembly in miceSemantic proximity Read ↗

Molecular basis of the morphogenesis of sperm head and tail in miceSemantic proximity Read ↗

CCDC38 is required for sperm flagellum biogenesis and male fertility in miceSemantic proximity Read ↗

The lack of Tex44 causes severe subfertility with flagellar abnormalities in male miceSemantic proximity Read ↗

Absence of tektin 4 causes asthenozoospermia and subfertility in male miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.