Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IFT25, an intraflagellar transporter protein dispensable for ciliogenesis in somatic cells, is essential for sperm flagella formation†

18 Apr 2017

Abstract excerpt

Intraflagellar transport (IFT) is a conserved mechanism essential for the assembly and maintenance of most eukaryotic cilia and flagella. However, IFT25, a component of the IFT complex, is not required for the formation of cilia in somatic tissues. In mice, the gene is highly expressed in the testis, and its expression is upregulated during the final phase when sperm flagella are formed. To investigate the role...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Kidney Cyst Diseases
Share to Renal and related cancers
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28430876
DOI: 10.1093/biolre/iox029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IFT25, an intraflagellar transporter protein dispensable for ciliogenesis in somatic cells, is essential for sperm flagella formation†PMID 28430876Read ↗

The essential role of intraflagellar transport protein IFT81 in male mice spermiogenesis and fertilitySemantic proximity Read ↗

Intraflagellar transporter protein 140 (IFT140), a component of IFT‐A complex, is essential for male fertility and spermiogenesis in miceSemantic proximity Read ↗

Murine germ cell-specific disruption of Ift172 causes defects in spermiogenesis and male fertilitySemantic proximity Read ↗

Intraflagellar transport protein 74 is essential for mouse spermatogenesis and male fertility by regulating axonemal microtubule assembly in miceSemantic proximity Read ↗

Intraflagellar transport is essential for mammalian spermiogenesis but is absent in mature spermSemantic proximity Read ↗

IFT25 is required for the construction of the trypanosome flagellumSemantic proximity Read ↗

Bi-allelic mutation in Fsip1 impairs acrosome vesicle formation and attenuates flagellogenesis in mice.Semantic proximity Read ↗

The cilia and flagella associated protein CFAP52 orchestrated with CFAP45 is required for sperm motility in miceSemantic proximity Read ↗

Ift25 is not a cystic kidney disease gene but is required for early steps of kidney development.Semantic proximity Read ↗

Essential Role of CFAP53 in Sperm Flagellum BiogenesisSemantic proximity Read ↗

Coiled-coil domain-containing 38 is required for acrosome biogenesis and fibrous sheath assembly in miceSemantic proximity Read ↗

Essential role of CFAP53 in sperm flagellum biogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.