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Article

Antigen-specific human NKT cells from tuberculosis patients produce IL-21 to help B cells for the production of immunoglobulins.

Oncotarget - 6 Oct 2015

Wu Changyou, Li Zitao, Fu Xiaoying, Yu Sifei, Lao Suihua, Yang Binyan

Abstract excerpt

Natural killer T (NKT) cells from mouse and human play an important role in the immune responses against Mycobacterium tuberculosis. However, the function of CD3(+)TCRvβ11(+) NKT cells at the local site of M. tuberculosis infection remains poorly defined. In the present study, we found that after stimulation with M. tuberculosis antigens, NKT cells isolated from tuberculosis (TB) pleural fluid mononuclear cells...

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Identifiers

PMID: 26416419
DOI: 10.18632/oncotarget.5764
PMCID: PMC4745682

Genes

CXCR5
CCR7
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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