Article
Differentiation and recruitment of Th9 cells stimulated by pleural mesothelial cells in human Mycobacterium tuberculosis infection.
PloS one - 1 Jan 2012
Ye Zhi-Jian, Yuan Ming-Li, Zhou Qiong, Du Rong-Hui, Yang Wei-Bing, Xiong Xian-Zhi, Zhang Jian-Chu, Wu Cong, Qin Shou-Ming, Shi Huan-Zhong
Abstract excerpt
Newly discovered IL-9-producing CD4(+) helper T cells (Th9 cells) have been reported to contribute to tissue inflammation and immune responses, however, differentiation and immune regulation of Th9 cells in tuberculosis remain unknown. In the present study, our data showed that increased Th9 cells with the phenotype of effector memory cells were found to be in tuberculous pleural effusion as compared with blood....
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