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Cytotoxic granules and effector molecules from immune cells in tuberculosis: Mechanisms of host defense and therapeutic potential

18 Aug 2025

Abstract excerpt

Tuberculosis (TB), a disease caused by Mycobacterium tuberculosis (Mtb), remains one of the most formidable infectious diseases globally. The immune system orchestrates a complex response including, but not limited to, T lymphocytes, natural killer (NK) cells, macrophages, and dendritic cells (DCs) to control and eliminate Mtb. While these cells are well-recognized for their roles in anti-tumor immunity, their...

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PMID: 40825006
DOI: 10.1080/21505594.2025.2542466

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