Article
DSEATM: drug set enrichment analysis uncovering disease mechanisms by biomedical text mining.
Briefings in bioinformatics - 18 Jul 2022
Luo Zhi-Hui, Zhu Li-Da, Wang Ya-Min, Hu Qian Sheng, Li Menglu, Zhang Wen, Chen Zhen-Xia
Abstract excerpt
Disease pathogenesis is always a major topic in biomedical research. With the exponential growth of biomedical information, drug effect analysis for specific phenotypes has shown great promise in uncovering disease-associated pathways. However, this method has only been applied to a limited number of drugs. Here, we extracted the data of 4634 diseases, 3671 drugs, 112 809 disease-drug associations and 81 527...
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